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Dosing and administration of ready-to-use CARDENE® I.V. (nicardipine hydrochloride)

Ready-to-use CARDENE I.V. is available in formulations of 0.2 mg/mL (40 mg in 200 mL) and 0.1 mg/mL (20 mg in 200 mL) in either sodium chloride or dextrose solutions and is administered as a continuous intravenous infusion.1

See CARDENE I.V. in a Clinical Setting

Watch CARDENE I.V. in a clinical setting to learn more about its dosing & administration.

Convenient dosing for RAPID or GRADUAL control

For Rapid Titration1 For Gradual Titration1
Initiate at 5 mg/hr* Initiate at 5 mg/hr*
If necessary, may increase by 2.5 mg/hr to a maximum dose of 15 mg/hr If necessary, may increase by 2.5 mg/hr to a maximum dose of 15 mg/hr
Titrate q 5 min Titrate q 15 min
Adjust infusion rate as needed to maintain desired response Adjust infusion rate as needed to maintain desired response

*Dosage for initiation of therapy in a patient not receiving oral nicardipine.
Following achievement of BP goal, decrease infusion rate to 3 mg/hr.

Administration of ready-to-use CARDENE I.V.

Converting Dose to Infusion Rate1

Dose (mg/hr) 20 mg in 200 mL
(0.1 mg/mL) Infusion Rate (mL/hr)
40 mg in 200 mL
(0.2 mg/mL) Infusion Rate (mL/hr)
3 30 15
5* 50 25
7.5 75 37.5
10 100 50
12.5 125 62.5
15 150 75

See full prescribing information for complete administration steps
*Dosage for initiation of therapy in a patient not receiving oral nicardipine.

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